Kidney

N(6)-carboxymethyllysine is an advanced glycation endproduct. It is associated with renal failure.

Possible AGE breaker to help restore kidney function: alagebrium.

Please look for more.

Article about podocytes -- a specialized type of epithelial cell in the kidney and re-generation:

http://www.eurekalert.org/pub_releases/2011-12/sumc-ros120211.php

Nephrons

"How might AGEs cause age-related damage in the kidney and other tissues? One mechanism might involve AGE-induced production of matrix metallproteases (MMPs) by fibroblasts. MMPs are known to break down the extracellular matrix, weakening the structural integrity of a tissue and also promoting metastatic invasion by cancer cells."

http://ouroboros.wordpress.com/2008/05/29/ages-in-the-kidney/

http://www3.interscience.wiley.com/journal/119397663/abstract?CRETRY=1&SRETRY=0

sources:

http://en.wikipedia.org/wiki/Carboxymethyllysine CML Carboxymethyl-Lysine -Published Data Demonstrating Elevation of Carboxymethyl-Lysine (CML) Is Associated with Decline in Renal Function and Arterial Stiffness in Older Adults

http://en.wikipedia.org/wiki/Carboxymethyllysine

http://www.alteon.com/therapeutics/alagebrium

Erythropoietin (EPO) is created and released by the kidneys. http://www.sciencedaily.com/releases/2007/09/070920111345.htm

page about kidney infection